Group Leader, Antibody–Oligo Conjugates (AOC)
You are an experienced bioconjugation or AOC‑focused scientist who thrives in discovery. You know how to design, implement, and optimise antibody–oligo conjugates, build assays, validate constructs, and move programmes toward candidate selection. You want to lead a function, build a team, and shape an emerging therapeutic platform from the ground up.
A newly established RNA‑therapeutics initiative is scaling rapidly and now seeks a Group Leader, Antibody–Oligo Conjugates to lead AOC engineering, bioconjugation workflows, assay development, and cross‑functional integration. The programme is expanding from 13 to ~80 scientists and needs leaders who “make things happen,” build systems, and deliver progress at pace.
THE ROLE
You will lead the AOC engineering and bioconjugation strategy, implementing antibody‑based tissue‑targeting approaches while simultaneously building the team around you. Your work ensures that AOCs move efficiently from design → conjugation → assay → validation → pre‑candidate stage.
This is a discovery‑heavy, hands‑on scientific leadership role where you define how the entire AOC workflow operates.
KEY RESPONSIBILITIES
Lead AOC engineering for tissue‑targeting applications, including design and implementation of conjugation strategies
Build complete flow‑schemes for AOC discovery; from design through screening, validation, and selection
Own bioconjugation strategy and oversee the work of a Bioconjugation Scientist/Senior Scientist
Oversee antibody generation, CRO interactions, and characterisation of known binders
Act as a scientific leader, problem‑solver, and “good citizen” within a multicultural, startup‑style team
ABOUT YOU
Strong background in bioconjugation, ADC/AOC engineering, or related antibody–nucleic acid modalities
Deep experience developing assays, validating conjugates, and understanding toxicity vs non‑toxicity mechanisms
Ability to run full discovery flow‑schemes and drive programmes toward candidate selection
Built and managed teams.
LOGISTICS
Full‑time, on‑site in Singapore
Visa sponsorship available
Very competitive benifits structure; relocation support available
Effective income tax typically 18–19% (max 24%)
Competitive Annual Salary
If you want to build a next‑generation AOC platform inside a rapidly scaling discovery organisation, Apply now!